AI|ffinity

AI|ffinity is a spin-off from CEITEC at Masaryk University in Brno, with facilities in Prague. Its unique platform combines nuclear magnetic resonance (NMR), artificial intelligence (AI), and cheminformatics to accelerate drug discovery and protein engineering. Specializing in hit discovery and hit-to-lead optimization, AI|ffinity decodes protein–ligand interactions from 1D NMR data and advances structure determination using 3D and 4D NMR with AI-driven analysis. The platform excels with proteins over 20 kDa and intrinsically disordered proteins, increasing success rates and reducing costs.